RNA
Part:BBa_K4173026:Design
Designed by: Haoyu Sun Group: iGEM22_NJU-China (2022-10-09)
loop
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
none
Source
The selection of this structure is based on previous research in our laboratory, and it is proved to be an effective siRNA expression system.
References
Fu Z, Zhang X, Zhou X, Ur-Rehman U, Yu M, Liang H, Guo H, Guo X, Kong Y, Su Y, Ye Y, Hu X, Cheng W, Wu J, Wang Y, Gu Y, Lu SF, Wu D, Zen K, Li J, Yan C, Zhang CY, Chen X. In vivo self-assembled small RNAs as a new generation of RNAi therapeutics. Cell Res. 2021 Jun;31(6):631-648. doi: 10.1038/s41422-021-00491-z. Epub 2021 Mar 29. PMID: 33782530; PMCID: PMC8169669.