RNA

Part:BBa_K4173026:Design

Designed by: Haoyu Sun   Group: iGEM22_NJU-China   (2022-10-09)


loop


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

none


Source

The selection of this structure is based on previous research in our laboratory, and it is proved to be an effective siRNA expression system.

References

Fu Z, Zhang X, Zhou X, Ur-Rehman U, Yu M, Liang H, Guo H, Guo X, Kong Y, Su Y, Ye Y, Hu X, Cheng W, Wu J, Wang Y, Gu Y, Lu SF, Wu D, Zen K, Li J, Yan C, Zhang CY, Chen X. In vivo self-assembled small RNAs as a new generation of RNAi therapeutics. Cell Res. 2021 Jun;31(6):631-648. doi: 10.1038/s41422-021-00491-z. Epub 2021 Mar 29. PMID: 33782530; PMCID: PMC8169669.